Route-specific assessment
Oral, dermal and inhalation routes are assessed separately.
Quality of the value
Distinguish tests, conversions and missing information.
Unknown components
Do not invent values for fractions without data.
Units and physical form
Duration, unit, dust, mist and vapour must correspond.
Interpretation
Compare the result with criteria and record assumptions.
Calculation control
An oral calculation uses only verified oral concentrations and ATE values.
Checklist
Route identified
Compatible units
Correct concentrations
Values sourced
Unknown fraction handled
Common mistakes
×mixing exposure routes
×using any available LD50
×ignoring active content
×rounding too early
Frequently asked questions
Does one ATE cover every route?
No. Each route uses its own evidence set.
Can a missing value be invented?
No.
Does a general answer validate a specific product?
No. The actual composition, form, supplier data and intended use must be assessed.
Who should approve the result?
A competent person should review the data, method and internal consistency before supply.
Primary sources
Check the current consolidated version and the exact substance or product scope before use.